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5 Things to Know About Adding Pramiracetam Powder to Your Daily Routine

pramiracetam powder

About 40% of people ages 65 and older have age-associated memory impairment. In the United States, that’s about 16 million people. About 15% develop Alzheimer’s, while 1% develop other types of dementia.

For some people, the thought of losing their memory is terrifying. What if you could enhance your long-term memory with a daily pill or powder instead?

Enter pramiracetam powder! Pramiracetam powder could help improve your memory. As a result, it could allow you to hold onto your unique experiences and history.

What exactly is pramiracetam, and how can it help?

Keep reading to discover the five things you need to know about this nootropic! By reading this guide, you could discover a way to improve your brain health and preserve your memories.

1. What Is Pramiracetam? 

Before you add pramiracetam powder to your daily routine, it helps to know exactly what it is.

Scientists developed pramiracetam in the late 1970s from piracetam. Piracetam is a nootropic agent. In fact, it was the first drug that scientists ever labeled a nootropic.

This agent reportedly enhanced memory and learning. It was also used to:

  • Treat motion sickness
  • Prevent hypoxia- and electroshock-induced amnesia
  • Help with learning

Nootropics are natural or synthetic chemicals that can impact a person’s mental skills. Nootropics are available as prescription drugs and dietary supplements. For example, Ritalin is a prescription nootropic used to treat ADHD.

Some nootropics are “cognitive enhancers.” These nootropics are able to enhance motivation, creativity, and intelligence. 

Not every chemical compound falls under the category of nootropics, though. Instead, these compounds must:

  • Enhance the memory
  • Have low toxicity levels
  • Create few side effects
  • Improve reactions under high levels of stress
  • Protect the brain from chemical or physical injury
  • Improve subcortical and cortical control

Using nootropics could improve a patient’s brain function. Which nootropic they use and the dose they take is important, though. 

Pramiracetam’s Early Uses

Scientists first tested pramiracetam on Alzheimer’s patients. Later, they used it on dementia patients as well. Scientists studied its effects on traumatic brain injuries and strokes, too.

Patients use pramiracetam for:

  • Dementia
  • Dyslexia
  • ADHD
  • Memory problems

You might find prescription pramiracetam under brand names like Remen, Neupramir, and Pramistar.

As a nootropic, pramiracetam is legal to use. In the US, it’s sold as an OTC research compound.

What Does It Do?

Pramiracetam powder should enhance your high-affinity choline uptake (HACU) in the hippocampus. It could also increase acetylcholine synthesis and function.

This ability allows pramiracetam to improve:

  • Learning
  • Focus
  • Memory
  • Recall

Pramiracetam doesn’t impact neurotransmitters like norepinephrine, dopamine, GABA, or serotonin. These neurotransmitters could influence your mood. In other words, pramiracetam can’t improve your mood or reduce anxiety levels.

This nootropic does increase nitric oxide activity in the brain, though. As a result, it could increase cerebral circulation. Increased cerebral circulation could help enhance the brain cells for:

  • Learning
  • Visual function
  • Motor function

When a patient uses pramiracetam, they might feel more alert. Their senses could sharpen, along with mental focus and clear thinking. Their long-term recall and memory formation could improve as well.

2. How Does It Work?

Remember, pramiracetam boosts your brain’s acetylcholine (ACh) synthesis. As a result, it can increase cerebral circulation. What exactly does that mean?

Nootropics like pramiracetam can cross the blood-brain barrier. Then, it influences the HACU system in your brain. HACU allows your synapses to use choline for ACh synthesis. The amount and efficiency of ACh should increase as a result.

Boosting your ACh levels can impact your memory and cognition abilities. ACh is a neurotransmitter that’s located throughout the body.

In the brain, it’s responsible for:

  • Encoding new memories
  • Cognition
  • Concentration
  • Reasoning
  • Growing new synapses

Without ACh, you could develop diseases like Alzheimer’s, ADD, or ADHD.

Once you take your pramiracetam powder, you might notice it’s easier to focus. The increased amount of ACh in your brain and hippocampus can enhance your learning abilities. Your ability to understand technical subjects could improve as well.

Meanwhile, the ACh could increase your neuroplasticity. Neuroplasticity is the brain’s ability to change its structure. For example, how many synapses you have between your neurons.

The neuron’s internal structure could change as well. As your neuroplasticity improves, your cerebral circulation should improve. This combination could affect long-term potentiation, which could help you recall long-forgotten memories.

How Does It Feel?

Your body might react to the pramiracetam experience differently than someone else’s. Most people claim it feels like your brain is firing on all cylinders immediately. In some cases, the ability to focus and think clearly could boost your confidence as well. 

This laser-like focus is ideal for long study sessions. It could also help with attention-based, logic-driven tasks that need attention to detail.

You might find it’s easier to work through long, arduous tasks. Since your level of cognition and focus improves, the tasks should no longer feel difficult.

Some people also say their ability to complete numerical calculations improves. You might have an easier time communicating. You might notice a change in your fluidity of thought and mental recall as well.

3. What Are the Potential Benefits?

Now that you know a little more about the pramiracetam experience, let’s talk about the potential benefits. Here are a few ways adding pramiracetam to your routine could benefit your overall life.

Might Affect Memory

Remember, pramiracetam is able to stimulate your hippocampus with higher ACh levels. It can also improve your neuroplasticity, which can help you remember long-forgotten memories. In other words, using pramiracetam powder could improve your reference memory.

By stimulating the hippocampus, pramiracetam could help you create new memories. At the same time, you’ll have an easier time retaining old memories. You could feel less forgetful as a result.

Over 5 million Americans are currently dealing with Alzheimer’s disease. Patients with Alzheimer’s experience damage to the brain long before their memory issues appear. Their cognitive function might not decline for a while as well.

While the initial symptoms can vary between patients, they often include:

  • Memory problems
  • Struggle to find the right words
  • Vision and spatial issues
  • Impaired judgment or reasoning
  • Increased anxiety
  • Increased aggression
  • Mood and personality changes
  • Repeating questions
  • Trouble paying bills and handling money
  • Getting lost or wandering
  • Losing or misplacing possessions
  • Taking too long to complete normal tasks

In later stages, patients can have a difficult time organizing their thoughts or thinking logically. They could also experience confusion, shortened attention span, and an inability to learn new things.

Taking pramiracetam early in life could improve your memory and reduce cognitive impairment. 

Might Have Neuroprotective Properties

As you get older, your brain chemistry will change. Age-related cognitive decline can include a decrease in:

  • Reaction time
  • Learning capacity
  • Acetylcholine receptors
  • Acetylcholine levels
  • Nitric oxide levels
  • Cerebral blood flow

Remember, taking pramiracetam could help your neurons. It might also protect your neurons, which could reduce cognitive decline.

Taking pramiracetam might reverse cognitive disorders. Patients who have suffered cerebrovascular brain trauma could benefit, too. Meanwhile, these patients won’t have to rely on scopolamine, which can actually cause cognitive decline. 

In one study, pramiracetam partially reduced memory loss caused by scopolamine. Scopolamine is a drug that can temporarily cause amnesia. In other words, pramiracetam might help protect the brain from dangerous drugs or toxins. 

Might Impact Recovery From Brain Injuries

There are a few studies that indicate pramiracetam could help the brain recover from a trauma or injury as well. For example, people with mild brain injury in this study experienced reduced:

  • Headaches
  • Nausea
  • Dizziness

These patients reported that pramiracetam was more effective than piracetam when treating their symptoms. Some patients said pramiracetam improved their memory, even after they sustained severe brain injuries.

Might Normalize Brain Waves

In this study, older rates had consistently different EEG profiles than those of younger rates. With the older rates, slow brain waves were present in the hippocampus and frontal cerebral cortex. Theta brain wave activity was missing, too.

Your theta brain waves are associated with the “ah-ha!” moment you might experience when coming up with a great idea. It’s also connected to:

  • Relief after a trauma
  • Integrative experiences
  • Creativity

Using pramiracetam helped normalize brain activity in the older rats. Meanwhile, its predecessor piracetam didn’t have the same effect.

Using pramiracetam could help normalize your brain waves. It might also help older patients improve their cognitive function and creativity.

Might Improve Learning Capacity

As a nootropic and cognitive enhancer, taking pramiracetam powder could benefit your learning capacity. Many people say it’s easier for them to grasp new concepts when using pramiracetam.

Remember, pramiracetam increases the activity of nitric oxide synthesis in your hippocampus. Nitric oxide is produced by every cell in your body. It works as a messenger between different organ systems.

Nitric oxide is mainly localized in the central nervous system. There, it influences synaptic transmission. It also contributes to your brain’s learning and memory abilities.

By increasing the supply of blood to your brain, it could boost neuronal activities.

Pramiracetam can help your central nervous system by boosting nitric oxide and ACH levels. By changing the brain’s computational ability, nitric oxide could help treat neurodegenerative diseases like Alzheimer’s.

However, more research is needed. 

4. What Are the Potential Side Effects?

Before you start taking any new medication or drug, it’s important to understand the side effects. Here are a few pramiracetam side effects you might experience.

It helps to know that pramiracetam is non-toxic. It is considered safe to use.

However, pramiracetam can cause headaches when it increases the ACh in your brain. You could take choline supplements to avoid this side effect.

Pairing pramiracetam with choline could improve your condition and memory. Some people say using pramiracetam impacts their emotions.

Other people experience:

  • Agitation
  • Gastrointestinal distress
  • Dizziness
  • Insomnia

To avoid side effects, make sure to consider your dosage before taking pramiracetam for the first time. 

5. How Do You Determine Your Dosage

Pramiracetam is not meant for one-time use. Instead, it’s designed for prolonged use.

Here are a few tips that can help you before using pramiracetam for the first time.

The Product Form

First, it helps to know that pramiracetam is a fat-soluble chemical. In other words, it’s designed to enter your bloodstream through a fatty acid.

You can take pramiracetam as a powder, capsule, or tablet. Between the three, pramiracetam powder acts the fastest. Capsules have a similar absorption rate. Tablets can take time before they enter your bloodstream.

Regardless of the form you choose, the potency and efficacy shouldn’t change.

Choline Levels

In order to experience effects, pramiracetam relies on choline. Otherwise, pramiracetam could deplete your body’s natural choline supply.

Remember, pramiracetam boosts your brain’s choline levels. Choline is necessary to boost acetylcholine. Acetylcholine provides your brain with the enhanced cognitive function you’re looking for.


Some people stack or combine nootropics to increase the effect. For example, you might consider using citicoline or Alpha GPC.

These options can supplement your body’s choline levels. They could also help you avoid a headache after taking pramiracetam.

Are you already taking any prescription stimulates? These can include nootropics like adrafinil or modafinil. You can combine your pramiracetam with these nootropics for complementary effects.

Pramiracetam could reduce any racing thoughts you experience by taking your medications. 


Consider starting at a low dose. Then, increase your dose over time until you experience effects. If you experience gastric upset or other side effects, lower your dose right away.

You can take pramiracetam with or without meals. Pramiracetam often comes with an unpleasant taste. You might want to take it with meals to mask the flavor.

How long does pramiracetam last? Pramiracetam effects could last between four to six hours. Its peak concentration and bioavailability occur during the first half-hour. 

Give Your Brain a Boost: Adding Pramiracetam Powder to Your Routine

Want to hack your brain and boost cognitive function? Consider adding pramiracetam powder to your daily routine. By using pramiracetam, you can give yourself an edge and feel smarter than ever. 

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These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.

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